- Torsion of the testis
- Torsion of a testicular appendage
- Epididymo-orchitis
- Mumps orchitis
- Acute hydrocele
- Idiopathic scrotal oedema
- Haematoma/haematocele
- Testicular neoplasm
- Henoch-Schonlein purpura
- Strangulated inguinoscrotal hernia
- Scrotal skin conditions
- Varicocele
- Referred pain (e.g. spine, ureteric colic, abdominal aorta)
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