Benign lymphocytic infiltrates

What is benign lymphocytic infiltrates?

• The are benign infiltrates of lymphocytes occurring in the dermis
• They are categorised into B cell and T cell proliferations. 
• Lymphocytoma cutis is the name used for B cell infiltrates
• Jessner's lymphocytic infiltrate is an example of a T-cell pseudo lymphoma 

How does it present?

• Rare
• The presentation is often in the third or fourth decade of life, but may occur at any age 
• They present as smooth red apple,es, plaques or nodules, which may be multiple and coalesce
• The face is most commonly involved, including the ear lobes

What the skin biopsy shows?

• moderately dense infiltrate lymphocytes within the dermis 
• distinction from lymphoma is sometimes difficult

What is the management?

• typical treatment includes
• potent topical steroids 
• intralesional steroids 
• phototherapy 
• hydroxychloroquine 
• spontaneous resolution sometimes occur 
• recurrence is common 
• small number may progress to lymphoma 

Reference:

• Primary certificate of dermatology RACGP