Wednesday, 27 January 2016

Acute Otitis Media

Condition

  • Acute Otitis Media 
Definition 
  • Middle ear infection 
  • The common organisms are viral (25%), streptococcus pneumonia, Haemophilus influenza and Moraxella catarrhalis 
Main features
  • Fever, irritability, otalgia and otorrhoea 
  • TM: translucency, colour, position and motility
  • self-limiting (60% of children treated with placebo became pain-free in 24 hours, and spontaneous resolution AOM occurs in approximately 80% of children)
  • According to eTG, diagnosis is likely if there is 
    • acute onset of signs and symptoms 
    • and a demonstrable middle ear effusion (MEE) characterised by any of the following:
      • Bulging of the tympanic membrane
      • Limited or absent movement of the tympanic membrane in response to changes in air pressure from a pneumatic otoscope
      • An air-fluid level behind the tympanic membrane
      • Perforation of the tympanic membrane with otorrhoea 
    • Signs and symptoms of middle ear inflammation, characterised by redness of the tympanic membrane
    • The incidence of mastoiditis in children with untreated AOM is 1: 1000
Management
  • Avoid the routine use of antibiotic therapy for acute otitis media
  • Initial antibiotic for all children with systemic features and may be required in children younger than 6 months without systemic features. The treatment recommendations apply regardless whether the tympanic membrane has perforated
  • Children without systemic features
    • In children aged 6 months or older --> observe, if symptoms persist more than 48 hrs, consider antibiotic treatment
    • In children aged younger than 6 months --> treat with antibiotic
  • Children with systemic features
    • amoxycillin 15 mg/kg up to 500 mg orally, 8 hourly for 5 days
    • or (for patients suspected to be non adherent) amoxycillin 30 mg/kg to 1 g orally, 12 hourly for 5 days
    • Patients who have an inadequate response to amoxycillin therapy within 48 to 72 hours may have infection caused by a beta-lactamase- producing strain of H. influenza or M. catarrhalis, adding clavulanate provides increased cavity against these pathogens. Use
      • Amoxycillin + clavulanate 22.5 + 3.2 mg/kg up to 500 + 125 mg orally, 8 hourly for 5 to 7 days
    • For patients hypersensitive to penicillins use 
      • cefuroxime (child 3 months to 2 years: 10mg/kg up to 125mg; 2 years or older: 15mg/kg up to 500 mg) orally, 12 hourly for 5 days
      • trimethoprim + sulfamethoxazole (child 1 month or older) 4 + 20 mg/kg up to 160 + 800 mg orally, 12 hourly for 5 days 
References
  • eTG

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