Tuesday, 26 January 2016

Intersitial lung diseases

Condition

  • Interstitial lung disease 
Definition
  • Interstitial lung diseases comprise a group of disorders that have the common features of inflammation and fibrosis of the inter alveolar septum, representing a non-specific reaction of the lung to injury of various causes
Main features
  • Dyspnoea and dry cough
  • fine inspiratory crackles at lung base
  • finger clubbing 
  • PFTs
    • restrictive ventilatory deficit
    • decrease in gas transfer factor
  • Characteristic x-ray changes
Causes
  • sarcoidosis
  • cryptogenic fibrosing alveolitis
  • extrinsic allergic alveolitis
  • drug induced
  • lymphangitis carcinomatosis
  • acute pulmonary oedema
  • immunological 
Treatment
  • Depends on cause

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