Monday, 25 January 2016

Approach to dysphagia

Approach to dysphagia 


Murtagh's diagnostic models 

** Excluding oropharyngeal infections and strokes**
** Although dysphagia is a common psychogenic symptom, it must always be taken seriously and investigated.**

Probability diagnosis 


  • Functional 
  • Tablet-induced irritation 
  • Pharynotonsillitis
  • Reflux oesophagitis

Serious disorders not to be missed 

  • Neoplasia
  • AIDS (opportunistic oesophageal infection)
  • Stricture, usually benign peptic stricture
  • Scleroderma
  • Neurological causes:
    • pseudobulbar palsy
    • multiple sclerosis 
    • motor neurone disease (amyotrophic sclerosis) 
    • Parkinson disease

Pitfalls (often missed)

  • Foreign body 
  • Drugs
  • Subacute thyroiditis
  • Extrinsic lesion (lymph nodes, goitre)
  • Upper oesophageal web (e.g. Plummer-Vinson syndrome)
  • Eosinophlic oesophagitis
  • Radiotherapy
  • Achalasia
  • Upper oesophageal spasm 
  • Globus sensation 
  • Rarities 
    • sjogren syndrome
    • aortic aneurysm
    • aberrant right subclavian artery
    • lead poisoning 
    • cervical osteoarthritis (large osteophytes)
    • other neurological causes
    • other mechanical causes
Red Flag Pointers 
  • Age > 50 
  • Recent or sudden onset
  • unexplained weight loss
  • Painful swalloing 
  • Progressive dysphagia 
  • Dysphagia for solids 
  • Hiccoughs
  • Hoarseness
  • Neurological symptom/signs 


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