Probability diagnosis
- Stress and anxiety
- Depression
- Viral/postviral infection
- Sleep-related disorder (e.g. sleep apnoea)
Serious disorders not to be missed
- malignant disease
- cardiac arrhythmia (e.g. sick sinus syndrome)
- cardiomyopathy
- anaemia
- hidden abscess
- haemochromatosis
- HIV infections
- Hepatitis C
Pitfalls
- 'Masked' depression
- Food intolerance
- Coeliac disease
- Chronic infection (e.g. lyme disease)
- Incipient CCF
- Fibromyalgia
- Lack of fitness
- Drugs: alcohol, prescribed, withdrawal
- Menopause syndrome
- Pregnancy
- Neurological disorders
- post-head injury
- CVA
- Parkinson disease
- Kidney failure
- Metabolic (e.g. hypokalaemia, hypomagnesaemia)
- Chemical exposure (e.g. occupational)
- Rarities
- Hyperparathyroidism
- Addison disease
- Cushing syndrome
- Narcolepsy
- Multiple sclerosis
- Autoimmune disorders
Minimal investigations from John Murtagh General practice 5th edition:
- FBE
- ESR/CRP
- TFTs
- Coeliac serology
- LFT
- CMP
- BSLs
- Iron studies
- Urine MCS
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